projects

Selected research and software projects in statistical genomics, spatial transcriptomics, and biomedical data science.

featured

IsoVita: Isoform Trajectories

Manuscript in preparation

An interpretable statistical framework for finding gradual and abrupt changes in transcript isoform usage across the human lifespan.

Cross-Donor Generalization

Manuscript in preparation

Testing how evaluation design changes estimates of cell-type classifier performance on unseen donors.

Homozygous Deletion Detection

QSURE 2026 · Research follow-up

Finding small, rare deletions in sparse single-cell DNA data by pooling evidence across cells.

SpotSweeper-py: Spatial QC

Published · F1000Research 2026

Open-source Python tools for detecting local quality-control outliers in spatial omics data.

Isoform Markers of Brain Aging

Conference poster · Biology of Genomes 2026

Using transcript isoform patterns to study brain aging and compare markers across brain regions.

Visium HD Analysis Workflows

Research software

Reusable Python workflows for quality control, artifact correction, and tissue-aligned visualization of high-resolution spatial transcriptomics.